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ALL ABOUT MS Treatment (Part 12)

ALL ABOUT MS  Treatment (Part 12)

The influence of infections and vaccination on the progression of multiple sclerosis


Infections that most often contribute to the deterioration of multiple sclerosis are in most cases of viral infection of the upper respiratory tract. Multiple sclerosis sufferers have two to three times the risk of exacerbating the disease if they are infected with viruses, causing these infections. In several recent studies, 30% of the worsening of the disease has been reported to occur in periods when respiratory infections are current. However, this does not mean that any viral infection will result in the deterioration of multiple sclerosis. In addition to viral infections, infectious agents such as chlamydia pneumoniae and mycoplasma pneumoniae can also contribute to the worsening of the disease.

In addition to general measures of protection against infections such as nutrition rich in vitamins and minerals, avoiding groups and staying in unprotected spaces, the best protection against infections provides immunization with appropriate vaccines. The most commonly used vaccine against respiratory infections is the influenza vaccine.


In the past years there were significant dilemmas about the immunization of patients with multiple sclerosis. Namely, having in mind that multiple sclerosis is an immune-mediated disease, the question arises as to whether additional stimulation of the already damaged immune system can contribute to its inappropriate response and lead to a worsening of the disease. However, after large and very sophisticated epidemiological and clinical studies conducted in France and the United States involving a large number of subjects, it has been shown that for people suffering from multiple sclerosis, it is useful to vaccinate the influenza vaccine. It is also known that the vaccine does not represent absolute protection against influenza, but the clinical picture of the influenza vaccine is much milder and, as a rule, there are no complications. In this way, in patients with multiple sclerosis, the risk of deterioration of the underlying disease is significantly reduced.
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